Lymphology is understanding the lymphatic system
Review: New developments in clinical aspects of lymphatic disease. An abstract by Professor Mortimer PS, Rockson SG:
The lymphatic system is fundamentally important to cardiovascular disease, infection and immunity, cancer and probably obesity - the four major challenges in healthcare in the 21st century.
This Review will consider the manner in which new knowledge of lymphatic genes and molecular mechanisms has demonstrated that lymphatic dysfunction should no longer be considered a passive bystander in disease but rather an active player in many pathological processes and, therefore, a genuine target for future therapeutic developments. The specific roles of the lymphatic system in oedema, genetic aspects of primary lymphoedema, infection (cellulitis/erysipelas), Crohn's disease, obesity, cancer, and cancer-related lymphoedema are highlighted.
PMID: 24590276 [PubMed - indexed for MEDLINE] PMCID: PMC3938261 [Available on 2015/1/1
Professor Mortimer is a consultant dermatologist at St George's University Hospitals NHS Foundation Trust. His clinical interests are in lymphovascular medicine and especially lymphoedema. His research interests include breast cancer-related lymphoedema, the genetic basis of lymphatic anomalies/lymphoedema and lymphangiogenesis in melanoma.
We are 70% water. When unwanted fluid is collected from between the cells and enters the lymphatic system, it is then known as lymph fluid. From all over the body waste fluid has been collected by capillaries and carried along through vessels, via the lymph nodes for filtration, similar to your household waste pipes and a wastewater treatment plant.
Cleaned waste fluid travels up towards cysterna chyle a lymph collection sac at the base of the largest lymphatic vessel called the thoracic duct, which lies next to your spine. It then passes up through the diaphragm and enters into the blood circulation via a large vein, just above the heart. The clean lymph fluid now mixes back into our blood. Our body can collect, clean and filter up to 2.5 litres per day.
However, if there is a blockage, disruption or lack of muscle movement the body will show signs of fluid retention seen as swelling called oedema.
Functions of the spleen
Stress is toxic to our bodies!
Stress directly affects the spleen and protein levels in the lymphatic system which affects your heart rate and blood pressure. During stress, the spleen releases extra blood into the circulation and an extra protein called p34, which is a distinct Lactate DeHydrogenase (or LDH or LD).
LD is of medical significance because it is found extensively in body tissues, such as blood cells and heart muscle, as with other proteins it is used as a tissue-function marker as it is released during tissue damage and is a marker of common injuries and disease. This protein has been found in high levels in many human cancers and has been demonstrated to be an effective serum cancer marker. (Lymhoscintography)
DON`T GET STRESSED - IT REALLY CAN BE FATAL.
In the fetus and infant, the thymus seems to control the development of the lymph nodes and lymphoid tissue. If it is absent, death will result because of the failure of the immune processes. In adults, it is a source of fresh lymphocytes for immunity.
Lymph capillaries, vessels and how lymph moves
Functions of a lymph node